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fibamdp posted: "
Jueves 14 de abril de 2022, 12 horas (GMT-3, Argentina), 4 p.m. CET
Anabella Aguilera
Centre for Ecology and Evolution in Microbial Model Systems (EEMiS). Linnaeus University, Sweden
Anabella is from Argentina and has a B. Sc. " </span>
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<p style="direction:ltr;font-size:14px;line-height:1.4em;color:#444;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;margin:0 0 1em;text-align:center"><strong> Jueves 14 de abril de 2022, 12 horas (GMT-3, Argentina), 4 p.m. CET</strong></p>
<h2 style="margin:.4em 0 .3em;font-size:1.8em;text-align:center"><a style="color:#2585b2"><strong>Anabella Aguilera</strong></a></h2>
<p style="direction:ltr;font-size:14px;line-height:1.4em;color:#444;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;margin:0 0 1em;text-align:center">Centre for Ecology and Evolution in Microbial Model Systems (EEMiS). Linnaeus University, Sweden</p>
<p style="direction:ltr;font-size:14px;line-height:1.4em;color:#444;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;margin:0 0 1em">Anabella is from Argentina and has a B. Sc. in Biology, orientation Ecology, from Universidad Nacional de La Plata (2011). She did her posgraduate studies in INBIOTEC and FIBA (Fundación para Investigaciones Biológicas Aplicadas) in Mar del Plata, under the supervision of Dr Graciela Salerno, and obtained her PhD degree at the Universidad de Mar del Plata (2017). As a postdoctoral fellow at the same Center, she began studying Cell Death by Ferroptosis in Synechocystis together with Dr. María Victoria Martin, in the Cyanobacteria Group led by Dr. Salerno. For two years she has been doing postgraduate studies at the Linnaeus University, Sweden.</p>
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<p style="direction:ltr;font-size:14px;line-height:1.4em;color:#444;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;margin:0 0 1em">The talks will be ~30min and afterward, there will be time to get in contact with the speaker and ask questions in the Q&A session. </p>
<p style="direction:ltr;font-size:14px;line-height:1.4em;color:#444;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;margin:0 0 1em"><strong>Registration link on the website: </strong> <a style="color:#2585b2" rel="noreferrer noopener" href="https://world.us17.list-manage.com/track/click?u=ba77328e38d54279f6918af99&id=caf7be3fe2&e=d9b4e16a45" target="_blank">Register Here!</a><br><a style="color:#2585b2" href="https://www.synmikrobiologie.hhu.de/cyano-online-seminar.html" target="_blank">https://www.synmikrobiologie.hhu.de/cyano-online-seminar.html</a></p>
<p style="direction:ltr;font-size:14px;line-height:1.4em;color:#444;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;margin:0 0 1em"><a style="color:#2585b2" href="https://us02web.zoom.us/meeting/register/tZcufuCrrj0jGtCdC36CXlRy7Bto4_N85jus" target="_blank">https://us02web.zoom.us/meeting/register/tZcufuCrrj0jGtCdC36CXlRy7Bto4_N85jus</a></p>
<p style="direction:ltr;font-size:14px;line-height:1.4em;color:#444;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;margin:0 0 1em"><strong><em>About the Seminar</em></strong>: "In contrast to accidental cell death, regulated cell death (RCD) is a genetically encoded signaling cascade that culminates in cell suicide and can be activated as the final step of cell differentiation or induced upon biotic orabiotic stress. In cyanobacteria, RCD is suggested to play a key role in developmental processes, such as akinete and heterocyst differentiation. Also, evidence has accumulated on RCD mechanisms triggered under unfavorable environmental conditions. However, our understanding of the underlying mechanisms and molecular machinery underpinning cell death in cyanobacteria remains largely limited."</p>
<p style="direction:ltr;font-size:14px;line-height:1.4em;color:#444;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;margin:0 0 1em">In this talk, Anabella will review the recent findings working with the model cyanobacterium <em>Synechocystis </em>PCC 6803 (<strong>Aguilera & Berdun</strong> <strong>et al., 2022</strong>). In this article, it is described a novel cell death program induced by heat stress with features resembling eukaryotic ferroptosis. Cyanobacterial ferroptosis is suppressed by the canonical ferroptosis inhibitors and by the addition of the antioxidant glutathione and ascorbic acid. This pathway is also characterized by an early depletion of both antioxidants and by lipid peroxidation. These results indicate that the main hallmarks of eukaryotic ferroptosis are conserved in cyanobacteria, and suggest that ferroptosis might be an ancient cell death program. Moreover, this work contributes to understandinghow cyanobacteria cope with environmental stress and activate RCD. Finally, I will present our next steps aiming to uncover mechanisms of stress response and RCD in bloom-forming cyanobacteria and assess their importance in bloom dynamics.</p>
<p style="direction:ltr;font-size:14px;line-height:1.4em;color:#444;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;margin:0 0 1em"><strong>Aguilera A</strong>, Berdun F, Bartoli C, Steelheart C, Alegre M, Bayir H, Yulia Y, Tyurina YY, Kagan VE, Salerno GL, Pagnussat G, Martin MV (2022). C-ferroptosis is an iron-dependent form of regulated cell death in cyanobacteria. Journal of Cell Biology 221: e201911005. doi:10.1083/jcb.201911005.</p>
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</tr></tbody></table><img alt="" border="0" src="http://pixel.wp.com/b.gif?blog=11462068&post=19916&subd=fibamdp&ref=&email=1&email_o=wpcom&host=public-api.wordpress.com" width="1" height="1"><img alt="" border="0" src="https://pixel.wp.com/t.gif?email_name=email_subscription&blog_id=11462068&_ut=anon&_ui=095546f9f74c5c26728bc1ba1fdd85d4&email_id=ebe2e7a60130c372214fc55973c3c1c4&date_sent=2022-04-01&domain=fibamdp.wordpress.com&frequency=0&digest=0&has_html=1&locale=en&_en=wpcom_email_open&browser_type=php-agent&_aua=wpcom-tracks-client-v0.3&blog_tz=0&blog_lang=en&_ts=1648815776565" width="1" height="1"></div>
</div><div>--<br></div></div></div><div dir="ltr" data-smartmail="gmail_signature"><strong>Dr. Ricardo Echenique<br></strong><font size="1">División Ficología "Dr. Sebastián Alberto Guarrera"<br>Facultad de Ciencias Naturales y Museo (UNLP)<br>Argentina<br></font><br></div></div>
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<td style="width:55px;padding-top:18px"><a href="https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail" target="_blank"><img src="https://ipmcdn.avast.com/images/icons/icon-envelope-tick-round-orange-animated-no-repeat-v1.gif" alt="" width="46" height="29" style="width:46px;height:29px"></a></td>
<td style="width:470px;padding-top:17px;color:#41424e;font-size:13px;font-family:Arial,Helvetica,sans-serif;line-height:18px">Libre de virus. <a href="https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail" style="color:#4453ea" target="_blank">www.avast.com</a> </td>
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